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mog35 55 peptide powder  (MedChemExpress)


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    Structured Review

    MedChemExpress mog35 55 peptide powder
    Mog35 55 Peptide Powder, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/mog35+55+peptide+powder/Calcium+chloride+anhydrous%2C+powder%2C+97%25/pm41265623-52-17-44
    Average 94 stars, based on 1 article reviews
    mog35 55 peptide powder - by Bioz Stars, 2026-09
    94/100 stars

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    Related Articles

    Adjuvant:

    Article Title: Oxymatrine regulates microglia to produce IFN-β by activating the STING/TBK1/IRF3 pathway against experimental autoimmune encephalomyelitis.
    Article Snippet: Oxymatrine is an alkaloid with the property of immunomodulation.. Recent studies have demonstrated that oxymatrine inhibits experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis (MS), by promoting the production of interferon-β (IFN-β).. However, the mechanism through which oxymatrine regulates the production of IFN-β remains unclear.

    Protein Concentration:

    Article Title: Oxymatrine regulates microglia to produce IFN-β by activating the STING/TBK1/IRF3 pathway against experimental autoimmune encephalomyelitis.
    Article Snippet: Oxymatrine is an alkaloid with the property of immunomodulation.. Recent studies have demonstrated that oxymatrine inhibits experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis (MS), by promoting the production of interferon-β (IFN-β).. However, the mechanism through which oxymatrine regulates the production of IFN-β remains unclear.

    Staining:

    Article Title: Oxymatrine regulates microglia to produce IFN-β by activating the STING/TBK1/IRF3 pathway against experimental autoimmune encephalomyelitis.
    Article Snippet: Oxymatrine is an alkaloid with the property of immunomodulation.. Recent studies have demonstrated that oxymatrine inhibits experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis (MS), by promoting the production of interferon-β (IFN-β).. However, the mechanism through which oxymatrine regulates the production of IFN-β remains unclear.

    SDS Page:

    Article Title: Oxymatrine regulates microglia to produce IFN-β by activating the STING/TBK1/IRF3 pathway against experimental autoimmune encephalomyelitis.
    Article Snippet: Oxymatrine is an alkaloid with the property of immunomodulation.. Recent studies have demonstrated that oxymatrine inhibits experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis (MS), by promoting the production of interferon-β (IFN-β).. However, the mechanism through which oxymatrine regulates the production of IFN-β remains unclear.



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    Thermo Fisher mog35-55 peptide lyophilized powder
    MAT ameliorated the severity of EAE. EAE was induced in female C57BL/6 mice by <t>MOG35-55</t> + CFA. Mice received MAT treatment (150 mg/kg in 100 μl normal saline per day, i.p. injection) from day 7 to day 19 p.i., and mice that received the same volume of saline served as control. (A) Clinical score was monitored as described in the “Materials and Methods” section. Data represent mean clinical score ± SD ( n = 10 mice per group). Mice were sacrificed on day 19 p.i., and spinal cords were harvested after extensive perfusion. (B) H&E staining was performed for detection of inflammation and Luxol fast blue (FLB) staining for demyelination. (C) Mean score of inflammation and demyelination. Data represent mean ± SD ( n = 10 mice per group). *** P < 0.001.
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    MAT ameliorated the severity of EAE. EAE was induced in female C57BL/6 mice by MOG35-55 + CFA. Mice received MAT treatment (150 mg/kg in 100 μl normal saline per day, i.p. injection) from day 7 to day 19 p.i., and mice that received the same volume of saline served as control. (A) Clinical score was monitored as described in the “Materials and Methods” section. Data represent mean clinical score ± SD ( n = 10 mice per group). Mice were sacrificed on day 19 p.i., and spinal cords were harvested after extensive perfusion. (B) H&E staining was performed for detection of inflammation and Luxol fast blue (FLB) staining for demyelination. (C) Mean score of inflammation and demyelination. Data represent mean ± SD ( n = 10 mice per group). *** P < 0.001.

    Journal: Frontiers in Immunology

    Article Title: Matrine Inhibits CNS Autoimmunity Through an IFN-β-Dependent Mechanism

    doi: 10.3389/fimmu.2020.569530

    Figure Lengend Snippet: MAT ameliorated the severity of EAE. EAE was induced in female C57BL/6 mice by MOG35-55 + CFA. Mice received MAT treatment (150 mg/kg in 100 μl normal saline per day, i.p. injection) from day 7 to day 19 p.i., and mice that received the same volume of saline served as control. (A) Clinical score was monitored as described in the “Materials and Methods” section. Data represent mean clinical score ± SD ( n = 10 mice per group). Mice were sacrificed on day 19 p.i., and spinal cords were harvested after extensive perfusion. (B) H&E staining was performed for detection of inflammation and Luxol fast blue (FLB) staining for demyelination. (C) Mean score of inflammation and demyelination. Data represent mean ± SD ( n = 10 mice per group). *** P < 0.001.

    Article Snippet: Myelin oligodendrocyte glycoprotein 35–55 (MOG35-55) peptide lyophilized powder (Invitrogen, California state, United States) was diluted to 3 mg/ml with 0.1 M PBS, emulsified with the same volume of complete Freud’s adjuvant (CFA) (Sigma, St. Louis, MO, United States) containing 4 mg/ml heat-killed mycobacterium tuberculosis H37RA (Becton, Dickinson and Company, NJ, United States).

    Techniques: Injection, Staining

    The effect of MAT was diminished by neutralizing anti-IFN-β mAb. EAE was induced in female C57BL/6 mice by MOG35-55, and received MAT and/or neutralizing anti-IFN-β mAb as described in the “Materials and Methods” section. Clinical score was monitored daily. (A) The mean clinical scores. Data represent mean clinical score ± SD ( n = 10 mice per group). (B) Mean cumulative clinical score obtained by adding the daily scores from the day of onset until the end of treatment for each mouse. Data represent cumulative clinical score ± SD ( n = 10 mice per group). Mice were sacrificed on day 19 p.i., and spinal cords were harvested after extensive perfusion. (C) H&E staining was performed for detection of inflammation and Luxol fast blue (FLB) staining for demyelination. (D) Mean score of inflammation and demyelination. Data represent mean ± SD ( n = 10 mice per group). ** P < 0.01, *** P < 0.001.

    Journal: Frontiers in Immunology

    Article Title: Matrine Inhibits CNS Autoimmunity Through an IFN-β-Dependent Mechanism

    doi: 10.3389/fimmu.2020.569530

    Figure Lengend Snippet: The effect of MAT was diminished by neutralizing anti-IFN-β mAb. EAE was induced in female C57BL/6 mice by MOG35-55, and received MAT and/or neutralizing anti-IFN-β mAb as described in the “Materials and Methods” section. Clinical score was monitored daily. (A) The mean clinical scores. Data represent mean clinical score ± SD ( n = 10 mice per group). (B) Mean cumulative clinical score obtained by adding the daily scores from the day of onset until the end of treatment for each mouse. Data represent cumulative clinical score ± SD ( n = 10 mice per group). Mice were sacrificed on day 19 p.i., and spinal cords were harvested after extensive perfusion. (C) H&E staining was performed for detection of inflammation and Luxol fast blue (FLB) staining for demyelination. (D) Mean score of inflammation and demyelination. Data represent mean ± SD ( n = 10 mice per group). ** P < 0.01, *** P < 0.001.

    Article Snippet: Myelin oligodendrocyte glycoprotein 35–55 (MOG35-55) peptide lyophilized powder (Invitrogen, California state, United States) was diluted to 3 mg/ml with 0.1 M PBS, emulsified with the same volume of complete Freud’s adjuvant (CFA) (Sigma, St. Louis, MO, United States) containing 4 mg/ml heat-killed mycobacterium tuberculosis H37RA (Becton, Dickinson and Company, NJ, United States).

    Techniques: Staining